Let's start with some local flavor:
This weekend (12/05/09) Midtown Yacht Club will be celebrating the repeal of Prohibition with a Toys for Tots toy collection/fundraiser. Period dress is encouraged. As an added bonus it will be held in the area (formerly?) known as the Spy Bar. Party starts at 9.
Also some idealistic young locals are trying to open a free "store". Good luck to them on that. (Their web site is having some issues at the moment so here's an alternate link.)
Now onto the international scene:
My new favorite charity ever? A Chilean prostitute is auctioning off 27 hours of adult fun times to help out her country's disabled children.